NanoSphere Health Sciences Form Strategic Partnership to Launch Evolve Products in Mexico

Agreement will bring the patented NanoSphere Delivery System™ to a
$5 billion market.

VANCOUVER (Dec. 10, 2018)– NanoSphere Health Sciences Inc. (CSE: NSHS) (OTC: NSHSF) (“NanoSphere” or “the Company”), the biotechnology leader behind the patented
NanoSphere Delivery System™, is pleased to announce the Company has signed a Letter of Intent forming a partnership with Abba Import Export S.A. de C.V., to launch Evolve’s growing product line in Mexico.

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Samuel TheilComment
NanoSphere Announces Revised Terms for Private Placement

DENVER--(BUSINESS WIRE)--NanoSphere Health Sciences, Inc. (CSE: NSHS) (OTC: NSHSF) announces revised terms for its non-brokered private placement previously announced on Nov. 16, 2018. The offering will consist of up to 7,500,000 units at a price of $0.30 per unit for gross proceeds of up to CAD $2,250,000. Each unit will be comprised of a common share and a full purchase warrant exercisable to purchase a further common share at a price of $0.50 cents for a period of 24 months, subject to accelerated expiry if the Company’s shares trade at or above $0.75 for 15 consecutive days.

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Nanosphere Announces $2.25 Million Financing for Rapid Expansion of Cannabis Product Line

DENVER (November 16, 2018)– NanoSphere Health Sciences Inc. (CSE: NSHS) (OTC: NSHSF) is pleased to announce a non-brokered private placement of up to CAD $2,250,000. The proceeds will be used to expand our award-winning Evolve Formulas cannabis products into more markets in the US, Canada, and outside of North America.  Funds will also be used to develop new products, increase production in the states that Evolve Products are available in, as well as for general working capital.

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Game-Changing Evolve Formulas Products Soon to Disrupt the Oregon Cannabis Market

—NanoSphere Health Sciences Signs Letter of Intent with Cascade Pure—

DENVER (November 13, 2018) – NanoSphere Health Sciences, Inc. (CSE: NSHS) (OTC: NSHSF), the biotechnology leader behind the patented NanoSphere Delivery System™, today signed a new letter of intent with Cascade Pure, LLC, which will bring Evolve Formulas products to the Oregon medical and recreational cannabis markets. The brand’s pioneering product, the Evolve Formulas Transdermal NanoSerum™, will hit dispensary shelves in the first quarter of 2019.

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Evolve Formulas Transdermal NanoSerum™ CBD Met with Unprecedented Response Across Colorado Market

—Industry-First Formulation Harnesses the Anti-Inflammatory Qualities of CBD and Antioxidant Power of Resveratrol for Maximum Wellness Benefits—

DENVER (November 7, 2018) – NanoSphere Health Sciences, Inc. (CSE: NSHS) (OTC: NSHSF), the biotechnology leader behind the patented NanoSphere Delivery System™, today announced the expansion of its CBD-dominant product—the Evolve Formulas Transdermal NanoSerum™ CBD with Resveratrol—across Colorado due to considerable public demand. The company has already moved more than 1,000 units in the market in less than a month.

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NanoSphere Health Sciences and Vertical Companies™ Commence Production in California

Award-Winning Evolve Formulas Transdermal NanoSerum™ To Hit Dispensary Shelves in the Golden State in Time for the Holidays

DENVER (October 10, 2018) – NanoSphere Health Sciences, Inc. (CSE: NSHS) (OTC: NSHSF), the biotechnology leader behind the patented NanoSphere Delivery System™, in partnership with Vertical™, the largest fully integrated company in the legal medical cannabis industry, has officially started production to bring its commercial cannabis brand, Evolve Formulas, into the California market.

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THE COMPLEX RELATIONSHIP BETWEEN CANNABIS AND MENTAL HEALTH

By Dr. Michele Ross

As the national dialogue surrounding cannabis continues to shift in favor of legalization, public knowledge of the plant’s health and wellness benefits is spreading, with many patients of mental illness discovering the potential of cannabis to relieve psychological distress and restore their ability to function in day-to-day life.

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Samuel Theil
NANOSPHERE HEALTH SCIENCES EXPANDS TO INDIANA WITH EVOLVE FORMULAS NANOSERUM™ HEMP

DENVER (September 11, 2018) – NanoSphere Health Sciences, Inc. (CSE: NSHS) (OTC: NSHSF), the biotechnology leader behind the patented NanoSphere Delivery System™, has entered into a revenue-sharing agreement to expand its Evolve Formulas product line to Indiana with Jeff DeHart, Managing Member of Evolve Formulas of Indiana, LLC. Under the agreement, NanoSphere will introduce a new, hemp-derived offering to the Indiana market.

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Samuel Theil
NanoSphere Health Sciences Wins Trio of ACQ5 Global Awards 2018

CEO Robert Sutton Recognized as Gamechanger of the Year; NanoSphere Named Company of the Year for Nano-Biotechnology and Innovative Company of the Year for Healthcare

DENVER (August 21, 2018) – NanoSphere Health Sciences INC (CSE: NSHS) (OTC: NSHSF), the nano-biotechnology company that has commercialized a patented delivery system known as the NanoSphere Delivery System™, has won three 2018 Global Awards from ACQ5, a premier global corporate magazine.

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Samuel Theil
Chairman's Letter

Dear Valued Shareholders,

Since our last update in April 2018, we have seen significant milestones for NanoSphere Health Sciences. We began the second quarter by announcing new licensing agreements to expand our Evolve Formulas brand into California and Arizona, followed by winning a prestigious award for technological innovation from Frost & Sullivan and retaining Gravitas Securities Inc as financial advisors.

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NanoSphere Health Sciences Partners with Delta 9 for Canadian Expansion

Biotech Leader’s Cannabis Division, Evolve Formulas, Prepares to Launch in Canadian Market

DENVER (July 31, 2018)- NanoSphere Health Sciences, INC (CSE: NSHS) (OTC: NSHSF), the biotechnology leader behind the patented NanoSphere Delivery System™, has entered into a partnership with Delta 9 Cannabis INC to bring products from its cannabis brand, Evolve Formulas, into the Canadian market.

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NanoSphere Health Sciences Secures Patent For Groundbreaking Nanoparticle Delivery of Cannabis

Denver (July 24, 2018) -- NanoSphere Health Sciences LLC (CSE: NSHS) (OTC: NSHSF) has been awarded a breakthrough patent, granting the biotech innovator full ownership over the standardized delivery of cannabis into systemic circulation through phospholipid nanoparticle technology. The United States Patent and Trademark Office has issued US Patent No. 10,028,919 today, covering NanoSphere Health Sciences’ cannabinoid drug delivery system

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NanoSphere Health Sciences’ Brand Evolve Formulas Partners with Former NHL Star Jeff Friesen

New Campaign Aims to Educate Athletes on Marijuana Healing Potential

DENVER (July 16, 2018)– NanoSphere Health Sciences INC (CSE: NSHS) (OTC: NSHSF), the biotech firm behind the groundbreaking NanoSphere Delivery System™, has announced that its cannabis brand Evolve Formulas will partner with Jeff Friesen, former NHL player and marijuana advocate, in a campaign to educate athletes about the benefits of cannabis as a natural health supplement.

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NanoSphere Health Sciences’ Brand Evolve Formulas Expanding Rapidly Across Colorado and Beyond

Next-Generation Cannabis Products Now Available in Over 200 Colorado Dispensaries, with Production Beginning in the California Market

NanoSphere Health Sciences INC (CSE: NSHS) (OTC: NSHSF), the biotech firm behind the groundbreaking NanoSphere Delivery System™, is experiencing a period of rapid growth for its cannabis brand, Evolve Formulas. The company has not only successfully expanded the product line to over 200 dispensaries in the Colorado market, but has also officially begun training and preparation for production in the California market.

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NanoSphere Health Sciences To Report Revenue and Sees Significant Sales Growth in Second Quarter

Biotech leader increases cannabis brand sales in Colorado by 30 percent ahead of California launch

DENVER (July 4, 2018)– NanoSphere Health Sciences INC (CSE: NSHS) (OTC: NSHSF), the biotech firm behind the cutting-edge patented NanoSphere Delivery System™ and the cannabis brand Evolve Formulas, today reports solid growth for this year’s second quarter.

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Dr. Michele Ross, Leading Cannabis Voice, Joins NanoSphere Health Sciences Team

Renowned Advocate and Scientist Takes on Medical Advisor Role for Evolve Formulas

DENVER, June 7, 2018 /PRNewswire/ -- Dr. Michele Ross, neuroscientist, author and cannabinoid medicine leader, has joined the advisory board for NanoSphere Health Sciences, LLC (CSE: NSHS) (OTC: NSHSF), the biotechnology leader behind the patented NanoSphere Delivery System™, which nano-encapsulates cannabinoid molecules in lipid membranes for transportation through the skin into the bloodstream within minutes.

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